raynaud condition score – Factors influencing Raynaud condition score diary outcomes

[PDF]

Raynaud’s Condition Score A PAtient-rePorted meAsure of diseAse severity The Raynaud’s Condition Score (RCS) is a scale that expresses the level of difficulty patients experience with Raynaud’s. Patients consider the frequency, duration, and severity of attacks to arrive at a single score expressed on a scale of zero to ten.

Feb 07, 2012 · The Raynaud’s condition score (box 3) is an ordinal score from 0-10 that measures the level of difficulty experienced by patients; it may help determine the impact of the condition on the patient’s functioning.

Cited by: 81
 ·

The Raynaud’s Condition Score (RCS) is a validated outcome measure used to assess the level of difficulty experienced due to RP each day (anchored from “no difficulty” to “extreme difficulty”)(3;4). It is administered either as a visual analog scale (VAS, 0–100) or

Cited by: 33
 ·

METHODS: Patients with SSc and moderate-to-severe RP participating in a multicenter RP treatment trial completed daily diaries documenting the frequency and duration of RP attacks and recorded a daily Raynaud’s Condition Score (RCS).

Cited by: 231

The minimally important difference and patient acceptable symptom state for the Raynaud’s condition score in patients with Raynaud’s phenomenon in a large randomised controlled clinical trial. MID, PASS, RCT, RP: 19 : 2009: Autologous progenitor cell implantation as a novel therapeutic intervention for ischaemic digits in systemic sclerosis. BM

In Raynaud’s disease, wrist pulses are typically normal but spasm of more distal arteries causes episodes of sharply demarcated pallor of the fingers. In Raynaud’s disease, wrist pulses are typically normal but spasm of more distal arteries causes episodes of sharply demarcated pallor of t

 ·

Nov 20, 2017 · A multicentre, placebo-controlled trial demonstrated benefit from a novel formulation of GTN, MQX-503, 46 in terms of improvement in Raynaud’s Condition Score. The trial included patients with PRP (n = 69) and secondary RP (n = 150, of whom 131 had SSc).

Cited by: 3
[PDF]

Raynaud’s Condition Score (RCS). The RCS is a daily self-assessment of RP activity using a 0–10 ordinal scale. The RCS incorporates the cumulative daily frequency, duration, severity, and impact of RP attacks. Details of the diary and a copy of the RCS data form

Cited by: 231
[PDF]

Please indicate the duration (in minutes) of each Raynaud attack that occurred today (if more than 15 attacks occur in one day please use a second page). Day Month Year

 ·

Improved Raynaud Condition Score, no change in duration or frequency of attacks: Headache, upper respiratory tract infection; dizziness: Prostaglandins: Epoprostenol: 1-2 ng/kg/min iv: 1: Decreased severity of symptoms in patients with scleroderma and pulmonary hypertension: Flushing, headache, nausea, vomiting, hypotension: Iloprost

Cited by: 19

Sep 19, 2018 · A total of 107 patients with SSc were enrolled between April 2005 and January 2017, and issued with a packet containing a questionnaire and a Raynaud’s Condition Score diary.

Mar 01, 2019 · Methods SSc patients were enrolled at UK and US sites. Participants completed the 2-week Raynaud Condition Score (RCS) diary alongside collection of patient demographics, clinical phenotype, the Coping Strategies Questionnaire, Pain Catastrophizing Scale, Scleroderma Health Assessment Questionnaire (SHAQ), and both patient/physician visual analog scale (VAS)

Cited by: 2
 ·

Mar 01, 2019 · Participants completed the 2-week Raynaud Condition Score (RCS) diary alongside collection of patient demographics, clinical phenotype, the Coping Strategies Questionnaire, Pain Catastrophizing Scale, Scleroderma Health Assessment Questionnaire (SHAQ), and both patient/physician visual analog scale (VAS) assessments for RP, digital ulcer

Cited by: 2
 ·

The minimally important difference and patient acceptable symptom state for the Raynaud’s condition score in patients with Raynaud’s phenomenon in a large randomised controlled clinical trial.

Cited by: 22
 ·

Mar 14, 2011 · Raynaud’s attacks: including frequency, severity, impact, and duration of symptoms (as assessed by patient diary); severity assessed by visual analogue scales, Likert scales, or the Raynaud’s Condition Score; digital ulceration, including rates, size, and healing

Cited by: 17

Oct 01, 2019 · Methods. SSc patients were enrolled at UK and US sites. Participants completed the 2-week Raynaud Condition Score (RCS) diary alongside collection of patient demographics, clinical phenotype, the Coping Strategies Questionnaire, Pain Catastrophizing Scale, Scleroderma Health Assessment Questionnaire (SHAQ), and both patient/physician visual analog scale (VAS)

Cited by: 2

Nov 11, 2019 · To cite this abstract in AMA style: Ruaro B, Alessandri E, Ghio M, Pizzorni C, Paolino S, Casabella A, De Tanti A, Sulli A, Cutolo M. Correlation Between Raynaud’s Condition Score, Nailfold Videocapillaroscopy and Laser Speckle Contrast Analysis in Secondary Raynaud’s Phenomenon Due to Systemic Sclerosis [abstract].

 ·

The minimally important difference and patient acceptable symptom state for the Raynaud’s condition score in patients with Raynaud’s phenomenon in a large randomised controlled clinical trial. Ann Rheum Dis 2010; 69:588. Roustit M, Giai J, Gaget O, et al. On-Demand Sildenafil as a Treatment for Raynaud Phenomenon: A Series of n-of-1 Trials.

 ·

Sep 27, 2002 · The Raynaud’s phenomenon (RP) attack diary consisted of 14 pages (measuring 11 × 15 cm) on which patients recorded the duration (in minutes) of each RP attack, the number of times they were exposed to outdoor temperatures, and the Raynaud’s Condition Score (RCS) each day for 14 days (Figure A). If more than 15 attacks of RP occurred in a given

Cited by: 231

Raynaud’s Condition Score (RCS): RCS is a daily self-assessment, graded on a scale of 0–10 based on the patient’s perceived impact of the frequency, duration, and severity of their RP (Fig. 17.1).This measure was developed by investigator consensus on the eve of a large-scale trial and was felt to offer an omnibus measure of patient perception of the impact of environmental cold and its

[PDF]

Raynaud’s phenomenon is an exaggerated vascular response to cold or stress manifested by skin colour changes at several locations, having three characteristic phases: pallor (white), cyanosis (blue) and rubor (red). When the cause is not known this phenomenon is termed primary Raynaud’s phenomenon

発表年:Revista de la Facultad de Medicina · 2014著者: Jairo Alonso Rodriguezcriollo · Daniel Jaramilloarroyave · Daniel Jaramilloarroyave提携:National University of Colombia · University of Caldas
 ·

The aim of this study was to assess the efficacy (in terms of improved VAS Pain, Raynaud’s Phenomenon attacks frequency and Raynaud’s Condition Score) of the Aminaftone in patients with Raynaud

Oct 22, 2018 · Exploratory efficacy endpoints included 1) change in Raynaud’s attacks from baseline to Week 14, assessed by the following individual outcome measures: Raynaud’s condition score (analyzed using ANOVA), patient/physician assessment of Raynaud’s phenomenon (analyzed using ANOVA), attack symptoms, attack duration, and average No. of attacks

 ·

Figure 2 shows the mean number and cumulative duration of Raynaud attacks in each 4-week treatment period and the mean daily Raynaud’s Condition Score during treatment with placebo and sildenafil in the 16 patients with secondary Raynaud’s phenomenon.

Cited by: 379
 ·

You have free access to this content Arthritis & Rheumatism Volume 46, Issue 9, Article first published online: 27 SEP 2002

発表年:Arthritis & Rheumatism · 2002著者: Peter A Merkel · Peter A Merkel · Karen Herlyn · Richard W Martin · Jennifer J Anderson提携:Harvard University · Boston University · Michigan State University · Wayne State Univ詳細情報: Systemic disease · Autoimmune disease · Immunopathology · Psychometrics · Rayna

The Raynaud condition score (RCS) that evaluates the limitation of daily activity on a scale from 1 to 10 (10 represents the total inability to do any activity) was used (Pope, 2011; Bose et al., 2015). Furthermore, the frequency (average number of event during the day) and duration (in minutes) of Raynaud’s attacks were also recorded.

Author: Barbara Ruaro, Carmen Pizzorni, Sabrina Paolino, Elisa Alessandri, Alberto Sulli

Oct 03, 2019 · Individuals with systemic sclerosis (SSc; n = 107) were recruited at UK and US sites in order to study the relative impact of a range of putative factors influencing the patient-reported evaluation of SSc-Raynaud phenomenon (RP) severity. Important connections between Raynaud Condition Score

The Raynaud’s Condition Score is presented in the diary that will be handed out to subjects for the duration of the study. The Raynaud’s Condition Score will ask subjects from a scale of 0 to 10, “0” being no difficulty, “10” being extreme difficulty, the number that best indicates the difficulty the subjects had each day with Raynaud’s condition.

Nov 21, 2018 · Change from baseline in the Raynaud’s Condition score (RCS). RCS is participant’s rating of difficulty considering number of attacks, duration, amount of pain, numbness, or other symptoms caused in the fingers (including painful sores) due to the Raynaud’s phenomenon every day and impact of Raynaud’s alone on use of hands every day.

Mar 25, 2019 · Instead, the study compared the mental health conditions of primary Raynaud’s sufferers to those with the secondary form – meaning those whose Raynaud’s is a by-product of a much more serious medical condition such as scleroderma, lupus, rheumatoid arthritis, MS, and other connective tissue and rheumatic diseases.

The clinical activity of Raynaud’s disease may be monitored using daily and weekly measures, including the Raynaud’s Condition Score (RCS).

 ·

Patient Perceptions of the Raynaud’s Condition Score Diary Provide Insight Into Its Performance in Clinical Trials of Raynaud’s Phenomenon: Comment on the Article by Denton et al. John D. Pauling BmedSci, BMBS, PhD, FRCP. Royal National Hospital for Rheumatic Diseases at Royal United Hospitals and University of Bath, Bath, UK.

Individuals with systemic sclerosis (SSc; n = 107) were recruited at UK and US sites in order to study the relative impact of a range of putative factors influencing the patient-reported evaluation of SSc-Raynaud phenomenon (RP) severity. Important connections between Raynaud Condition Score (RCS

The Raynaud’s Condition Score is presented in the diary that will be handed out to subjects for the duration of the study. The Raynaud’s Condition Score will ask subjects from a scale of 0 to 10, “0” being no difficulty, “10” being extreme difficulty, the number that best indicates the difficulty the subjects had each day with Raynaud’s condition.

Background The Raynaud’s condition score (RCS) is a validated outcome measure for Raynaud’s phenomenon (RP). Objective To assess the minimally important difference (MID) and patient acceptable symptom state (PASS) for RCS in patients with RP. Subjects and methods Patients with active RP (n=162) (mean RCS >25 (0–100 visual analogue scale) participated in a placebo-controlled, crossover

 ·

Aug 21, 2018 · Assessment of Raynaud’s phenomenon (RP) in systemic sclerosis (SSc) is reliant on self‐report. The Raynaud’s Condition Score (RCS) diary assumes discrete episodic RP attacks, although not all SSc patients identify with this paradigm.

Apr 18, 2008 · This disorder is referred to as Raynaud’s disease when the cause is unknown and Raynaud’s phenomenon when it is secondary to another condition. 1 It is characterized by attacks of vasospasm of digital arteries and arterioles that leads to intermittent pallor or cyanosis of the skin. It primarily affects the fingers, usually distal to the knuckles, and less commonly the toes.

Primary outcomes were changes in the Raynaud condition score (RCS), which was assessed daily by a standardized patient questionnaire, and digital blood flow, measured by the use of a laser Doppler perfusion imager, as previously described. 4 Secondary end points were safety and tolerability.

 ·

While taking sildenafil, the mean frequency of Raynaud attacks was significantly lower (35±14 versus 52±18, P=0.0064), the cumulative attack duration was significantly shorter (581±133 versus 1046±245 minutes, P=0.0038), and the mean Raynaud’s Condition Score was significantly lower (2.2±0.4 versus 3.0±0.5, P=0.0386).

 ·

Single item, part of other scales (such as overall disease, overall pain, or digital ulcer pain), or part of a multiquestion pain questionnaire. The Raynaud’s Condition Score (RCS) and Symptom Burden Index contain pain questions. There may be subscales of various pain

Raynaud’s phenomenon can be a difficult condition to diagnose because it has a complex set of causes, which may act by various different mechanisms, and signs and symptoms can vary.

[PDF]

Raynaud’s Condition Score. Subjects were asked to document the number and duration of Raynaud attacks and note the Raynaud’s Condition Score daily. The study was finished by a follow-up examination. The treatment with SLx-2101 failed to proof statistical significance measured by the primary

Mean Raynaud condition score (0-100) over a period 14 days Number of attacks [ Time Frame: 1,2,3,4,5 years ] Mean number of RP attacks per day over a period of 14 days

Jan 24, 2019 · Raynaud’s Condition score [ Time Frame: 3 months ] Assessment of Raynaud’s symptoms using the validated Raynaud’s Condition Score. This is a 1 to 10 Likert scale, with 0 representing ‘no difficulty’ and 10 indicating ‘extreme difficulty’ with symptoms; collected daily for 3 months, a lower score indicates a more favourable outcome.

 ·

The Raynaud’s condition score is a 11-point scale severity score used in Raynaud’s phenomenon clinical trials since 1998. The Raynaud’s condition score diary has been recommended for use in

 ·

The data from the best designed study show a reduced attack frequency and duration, reduced Raynaud Condition Score, and increased capillary blood flow in patients with secondary Raynaud’s phenomenon.

 ·

The Raynaud’s condition score is a 11-point scale severity score used in Raynaud’s phenomenon clinical trials since 1998. The Raynaud’s condition score diary has been recommended for use in clinical trials assessing efficacy of interventions on scleroderma related Raynaud’s phenomenon.

Raynaud’s is a rare disorder that affects the arteries. It is marked by brief episodes of narrowing of the blood vessels, reducing blood flow. Learn more about causes, risk factors, screening and prevention, signs and symptoms, diagnoses, and treatments for Raynaud’s, and how to participate in clinical trials.

In terms of Raynaud condition score at 10 weeks, patients taking Vardenafil had a reduced 0.13 reduced Raynaud condition score when compared to Amlodipine (95% CI -2.55 to 2.77). In terms of rank probability, Tadalifil had a 44% chance of being the option most likely to be associated with the lowest Raynaud condition score at 10 weeks.

 ·

The mean Raynaud’s Condition Score also was significantly lower — 2.2 versus 3.0. In all six patients with secondary Raynaud’s phenomenon and chronic digital ulcerations, trophic lesions began to visibly heal during sildenafil treatment. In two patients, ulcerations completely disappeared.

The Raynaud’s condition score is a 11-point scale severity score used in Raynaud’s phenomenon clinical trials since 1998. The Raynaud’s condition score diary has been recommended for use in clinical trials assessing efficacy of interventions on scleroderma related Raynaud’s phenomenon. However, this score has never been formally validated in French.

Mar 08, 2011 · Secondary endpoints, including Raynaud’s Condition Score, duration of attacks, and RP pain score, were not significantly different between the two groups. The most frequent adverse events reported were headache and indigestion with the majority of these events being mild or moderate.

 ·

Raynaud’s phenomenon (RP) is a transient, acral, vasospastic phenomenon that manifests with characteristic color changes. This vasospasm, classically triggered by cold temperatures, may also be driven by shifts in temperature, climate, or emotional state. Primary RP (PRP) is a common condition without severe sequelae.

Introduction Recent controlled trials have assessed the efficacy of phospodiesterase-5 (PDE-5) inhibitors in secondary Raynaud’s phenomenon (RP). However, the conclusions are conflicting, and whether these drugs are effective remains unclear. The objective of this meta-analysis was to determine the efficacy of PDE-5 inhibitors on Raynaud’s Condition Score (RCS) and frequency and duration of

Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma (TAMER) Participants will be patients with early diffuse systemic sclerosis and Raynaud phenomenon who have no history of cardiovascular disease or diabetes. A total of 30

 ·

Measures of systemic sclerosis (scleroderma): Health Assessment Questionnaire (HAQ) and Scleroderma HAQ (SHAQ), Physician‐ and Patient‐Rated Global Assessments, Symptom Burden Index (SBI), University of California, Los Angeles, Scleroderma Clinical Trials Consortium Gastrointestinal Scale (UCLA SCTC GIT) 2.0, Baseline Dyspnea Index (BDI) and Transition Dyspnea Index (TDI) (Mahler’s

What Causes Raynaud’s? National Heart Lung and Blood Institute. NIH. Factors influencing Raynaud’s condition score diary outcomes in systemic sclerosis. Patient–reported assessment of SSc–RP severity is associated with a number of factors including pain, catastrophisation and coping strategies. PubMed, J Rheumatol, 03/01/2019.

Statistics of Raynaud’s disease Map – Check how this condition affects the daily life of people who suffer it. Statistics of Raynaud’s disease Map – Check how this condition affects the daily life of people who suffer it. Total score of Raynaud’s disease: 1426 Total score ranges from 0 to 3,600 being 0 the worst and 3,600 the best.

Jan 11, 2017 · Cytori to Include Raynaud’s Phenomenon in Its Scleroderma Cell Therapy Program. January 11, 2017 January 11, 2017. and Raynaud’s Condition Score. Also, 83 percent of the patients had no symptoms of Raynaud’s in the weeks prior to each follow-up assessment, and maintained their improvement in hand strength and mobility scores since